Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects.
نویسندگان
چکیده
Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.
منابع مشابه
Cryoglobulinaemic vasculitis: new aspects.
Department of Rheumatology, University of Lübeck; Vasculitis Centre UKSH and Clinical Centre Bad Bramstedt, Lübeck, Germany. Please address correspondence to: Peter Lamprecht, MD, University of Lübeck, Department of Rheumatology, Vasculitis Centre UKSH and Clinical Centre Bad Bramstedt, Ratzeburger Allee 160, 23538 Lübeck, Germany. E-mail: [email protected] Received on January 19, 2012; a...
متن کاملPerformance of the preliminary classification criteria for cryoglobulinaemic vasculitis and clinical manifestations in hepatitis C virus-unrelated cryoglobulinaemic vasculitis.
BACKGROUND Cryoglobulinaemic vasculitis (CV) is often related to hepatitis C virus (HCV) infection, but it can develop in other diseases (e.g. other infections, connective tissue diseases, malignancies) in the absence of HCV infection. A comparison of the performance of the recently published classification criteria for the CV was made between HCV-positive and HCV negative patients with serum c...
متن کاملThe Place of Immunotherapy in the Management of HCV-Induced Vasculitis: An Update
Patients with chronic hepatitis C virus (HCV) can develop systemic cryoglobulinemic vasculitis. Combination of pegylated-interferon α and ribavirin is the first-line treatment of this condition. However, in case of severe or life-threatening manifestations, absence of a virological response, or autonomized vasculitis, immunotherapy (alone or in addition to the antiviral regimen) is necessary. R...
متن کاملPreliminary classification criteria for the cryoglobulinaemic vasculitis
BACKGROUND To develop preliminary classification criteria for the cryoglobulinaemic syndrome or cryoglobulinaemic vasculitis (CV). METHODS Study part I developed a questionnaire for CV to be included in the formal, second part (study part II). Positivity of serum cryoglobulins was defined by experts as an essential condition for CV classification. In study part II, a core set of classificatio...
متن کاملValidation of the classification criteria for cryoglobulinaemic vasculitis.
OBJECTIVE The aim of this study was to validate the classification criteria for cryoglobulinaemic vasculitis (CV). METHODS Twenty-three centres were involved. New patients with CV (group A) and controls, i.e. subjects with serum cryoglobulins but lacking CV based on the gold standard of clinical judgment (group B) and subjects without cryoglobulins but with clinical features that can be obser...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 83 976 شماره
صفحات -
تاریخ انتشار 2007